ASIO works awful on my end, I recommend against it. It's so much louder than anything else and I still can't change the volume. And it kills Skype.

This is only on my main production computer, though- makes no sense.
Anyway, just disable a few tracks using the little green thing at the left and export it as a WAV file. Then, reimport it and have that play. Much less CPU wasted, but a bit of HDD space. Hey, it's worth it, though.