When working primarily or solely with virtual instruments (and that includes voice!) you may have forgotten about their strengths and limitations and wind up writing something that would be unrealistic for an actual human performer. Maybe you're interested in writing for the viola d'amore or harp, but were unsure how to go about it. Or maybe you feel that your favorite instrument is criminally under-appreciated.
This thread is meant to help with that, to provide some pointers on instrumental composition, shed light on overlooked instruments, and perhaps inspire some people to make more creative use of them.
Playing the instrument yourself is preferable but not required. You can post about anything you feel deserves to be better understood.
Of course, not everyone has the best VSTs and even some high quality ones don't include every feature or technique. But it's still important for a composer to know as much about the instruments they're writing for as possible.
I'll provide an example of what I'm thinking of. It will be for the cello since that's what I'm most familiar with.
Cello/Violoncello
Range:

Favorite/notable solos and performances:
1. (Obligatory) Bach's Unaccompanied Cello Suites
2. Bruch's Kol Nidrei
3. Schubert's Piano Trio in E-flat major, 2nd mvt.
4. Boccherini's Complete Cello Concertos
Common mistakes and misconceptions:
The cello, like its string relatives, is capable of much more than playing just legato block notes. It can also do pizzicato, tremolo, double/triple/quadruple stops, col legno, con sordina, et al. It's much more than simply something to fill out the bass part! It has incredible range and is highly emotive, so make use of that! It is more than capable of leading a performance. For much of the western musical canon, violins were thought of as the primary solo instrument but thankfully since then the cello has garnered quite a few beautiful solos and a reputation for being an expressive instrument in its own right.
Dos and Don'ts:
Dos: Do vary! A common cellist complaint is parts that are too much like Pachelbel's Canon, and that goes for pretty much any instrument, really. Do make use of the cello's range. It can play many different octaves, and you can achieve a more unique and expressive sound make utilizing this feature. Do change dynamics. Volume is a pretty simple way of applying emotion and resonance. Plus, playing at the same dynamic the whole time gets boring for the performer. Do know and make use your instrumentation! If you're going to have a cello at all then it would be wise to know exactly what you're trying to achieve with it.
Don'ts: Don't write only block notes and chords. Those are quite dull to play and most of the time they're uninteresting for the listener to hear. But also don't write anything that is beyond human capability (such as constant hundred twenty-eighth notes at a super fast tempo or a double stop that would require the same string). Don't give the cello the exact same role as your other instruments. Just as you should vary your cello's role, you should vary all your roles so that it's more engaging for the listener.
Agree that this is a good idea, think that it's terrible, did I leave this out, am I dead wrong about that? By all means, say so!
My hope is to have a concentrated source where people don't have to scroll through pages and pages of nonessential posts to find the information that they're looking for. So, I'm thinking that if you're wanting to suggest edits to this post or someone else's then please send it as a PM instead.